Vaccines
Applying and Developing Tools for LNP Vaccine Formulation
Formulation Space: Lipids, PEG, Cholesterol, RNA length, Formulation process, Shelf life, Concentration, Transition through various cell barriers and conditions …
Vaccine results generated during the Covid19 pandemic
In a collaboration with Roche/Genentech seeking to contribute to developing lipid nanoparticles (LNPs) for vaccine and other future applications, the Taskforce 5 team developed a method to correlate structure to efficacy using high throughput SAXS.
Methods in Enzymology 2023, Frontiers in Molecular Bioscience 2024
Collection of SAXS data at high throughput
Collection of SANS data for novel contrast